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In abuse or overdose, subjects are consistently sedated and obtunded, frequently becoming comatose. Symptoms of overdose may include shallow breathing, clammy skin, dilated pupils, weak where can I order soma 250 mg Surprise and rapid pulse, paradoxical excitement and insomnia, convulsions and possibly death. Meprobamate overdose puedeproducir drowsiness, ataxia, severe respiratory depression, hypotension, shock, heart failure and death Duration of effect:. The effects of carisoprodol begin within 30 minutes after where can I order soma 250 mg Surprise oral administration and can last up to 4 - 6 hours.

In case of overdose, coma may last from several hours to a day or more. Meprobamate has effects carisoprodol much time due to tolerance much longer half-life, dependence and withdrawal:.

Development of abuse and moderate physical and psychological dependence can occur with chronic use of both carisoprodol and meprobamate. Abrupt discontinuation of where can I order soma 250 mg Surprise long-term use may be followed by mild withdrawal symptoms such as anxiety, abdominal cramps, insomnia, headache, nausea, vomiting, ataxia, tremors, muscle spasms, confusion, and sometimes , chills, convulsions and hallucinations. The early withdrawal of meprobamate occurs within 12-48 hours after cessation of use, and can last more than 12-48 hours. Carisoprodol has been shown to produce cross-tolerance to the drug interactions of barbiturates.

Alcohol increases the deterioration of his physical abilities produced by carisoprodol, and increased sedation, extreme weakness, dizziness, agitation, euphoria and confusion can be observed.

Alcohol also inhibits the metabolism of meprobamate and produces an additive depressant effect on the central nervous system, including drowsiness, disorientation, incoherence and confusion. Concurrent administration of other centrally acting drugs such as opiates, benzodiazepines, barbiturates and other muscle relaxants can where can I order soma 250 mg Surprise contribute to the deterioration. Meprobamate may enhance the analgesic effects of other performance-enhancing drugs:. Very limited studies of carisoprodol, however, a single oral dose of 700 mg has not been shown to affect psychomotor and cognitive tests within 3 hours of dosing, to a significant degree. In contrast, single doses of meprobamate are capable of causing significant performance impairment.

Performance effects include decreased divided attention, impaired coordination and balance, slowed reflexes and reaction time increased. With chronic administration of other where can I order soma 250 mg Surprise medicines, is likely to decrease in psychomotor performance would be even more pronounced effect on driving:. The drug manufacturer suggests that patients should be warned that carisoprodol and meprobamate can affect mental and / or physical ability required to perform potentially hazardous tasks such as driving a motor vehicle.

The signs of psychomotor and cognitive impairment reported in subjects found to be driving under the influence of carisoprodol / meprobamate include poor perception, reaction time impaired, driving slow, confusion, disorientation, inattentiveness, difficulty of speech or thick, slow responses, somnolence, lack where can I order soma 250 mg Surprise of balance and coordination, unsteadiness, and difficulty standing, walking or exiting vehicles. Loganet al., 2000 described 21 cases of driving under the influence where carisoprodol and / or meprobamate were the only drugs detected. The average concentrations were 4.6 meprobamate carisoprodol mg / L (range 0-15 mg / L) and 14.5 mg / L (range 1-36 mg / L), respectively.

Signs of deterioration were observed in blood levels as low as 1 mg / L of meprobamate, however, the inability to manage the symptoms most serious and obvious intoxication occurred in drivers and combined concentrations of carisoprodol meprobamate blood above 10 mg / L.